Natural products: Anti-fungal agents derived from plants

Tasleem Arif, T. K. Mandal and Rajesh Dabur, scientists at 

National Research Institue of Basic Ayurvedic Sciences Nehru Garden, Kothrud, Pune-411038, India published in 

Opportunity, Challenge and Scope of Natural Products in Medicinal Chemistry, 2011: 283-311 ISBN: 978-81-308-0448-4 

Abstract. As new spectrums of human fungal infections are increasing due to increased cancer and AIDS patients. The increased use of antifungal agents also resulted in the development of resistance to these drugs. It makes necessary to discover new classes of antifungal compounds to treat fungal infections. The research on natural products and natural products derived compounds has accelerated in recent years due to their importance in drug discovery. Plants are rich source of bioactive secondary metabolites of wide variety such as tannins, terpenoids, alkaloids, and flavonoids, reported to have in vitro antifungal properties. A series of molecules with antifungal activity against different strains of fungus have been found in plants, which are of great importance to humans and plants. These molecules may be used directly or considered as a model for developing better molecules. This review attempts to summarize the current status of reported antifungal compounds from plants. 

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September 27, 2012 · 4:03 pm

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