Any body who has a family member suffering from an auto-immune disease realizes the importance of research in immune biology. Severe allergy, Multiple sclerosis, Rheumatoid Arthritis, Crohn’s Disease, Lyme Disease, Osteoarthritis, and recently, Diabetes are a list of diseases that are related to a malfunction of the immune order in a body. The body begins to attack it’s own cells believing that it is a “foreign” cell or an invading organism that needs to be destroyed. The degeneration of parts of the body begins leading to specific disease. The New York Times covers the story of two scientists from two different countries who collaborated in the same lab to discover answers to the immune system. Read here to learn about: the seminal contributions of immunologists Charles A. Janeway Jr. (1943-2003) and Ruslan Medzhitov. Their work went unrecognized by the nobel committee. Now, you as the public must begin to award and recognize the scientists you value. Shower them with emails and let them know that you care about their research. Let them feel appreciated. Invite them for talks. Give them free dinners at talks – yes, scientists love that free cookie.
It is also well known that a strong immune system is capable of fighting disease. Monks from Tibet are being researched to teach the world how the mind can control the body’s immune system. A strong, happy person is invariab
ly a healthy person. A sad person, becomes depressed and begins to suffer from all kinds of ailments, many imagined and many real.
Click here to read about Prof Charles Janeway. His immunology course at Yale was legendary. He created more immunologists like himself by inspiration.
Click here to read about Dr. Ruslan Medzhitov. He arrived from Russia to work with Dr Charles Janeway, to prove his theory about the two fold immune system.
The immune system is two fold: The biological clock of the body controls the innate immune system – just like plants, all humans, animals and birds are conditioned by nature to wake up with the sun, have light exposure of several hours and then off to sleep by sunset or dark. Flowers close, birds stop chirping, animals begin to snore, but humans? Night shift workers have higher rates of illnesses. Could it be a biological clock gone awry?
The innate immune system controls the adaptive immune system which controls how we respond to microbes and environmental insults. When the biological clock is off, the innate immune system is off and since it controls the adaptive immune system, the response to body insult is off. Any wonder why unhappy people or those who work irregular hours feel sicker?
Which scientists should the public honor and thank for researching the innate and adaptive immune system and the way they are connected? You must read the following
A revolutionary idea of how the immune system worked. In vertebrates, two immune systems protect against infection. There’s the evolutionarily older system that all organisms, even plants, have — the innate immune system. There is also another system that evolved relatively recently, the adaptive immune system, which only vertebrates have. Janeway proposed that the innate system detects invading microbes, distinguishes them from everything else and signals the adaptive immune system to move against the intruder.
the authors of the paper did not get a nobel prize and the scientific community is very upset. They felt that the discovery of the toll receptors was worth a nobel prize. Read the New York Times article, “A long journey to the immune system” here.