Monthly Archives: April 2012

Cosmetic ingredients and hazards to health, including Allergy


A national TV news brought to our attention again today, April 30, 2012 that cosmetic ingredients are not monitored in all countries. In fact, Europe and Japan has more stringent rules than USA controlling what can go into cosmetics. Other countries? Safest option, if you must use cosmetics might be to use those with shortest label with fewest ingredients, concludes ABC news.

Some ingredients might be toxic like mercury, while others can cause allergic dermatitis, like toluene or cancer like formaldehyde. A woman’s cosmetic list selects from 120 chemicals, with some that might be dangerous introduced via the skin as a cream or lips via lipstick.

What is your opinion? Do you believe only safe chemicals should be used in cosmetics?
You might want to see the following sites to be more informed.
1) National TV ABC news: 2012
2) Toxic Cosmetic ingredients
3) Organic cosmetics the answer?

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Our site has been nominated for the Versatile Blogger Award.


Before I tell you about the versatile blogger nomination, may I request you to walk or speak for Autism in 2012. There are several organized events that you might join or you might create your own to raise awareness for need for intense Autism research. Click here for a list of Autism events in 2012.

Now, what is the versatile blogger award nomination? Basically, it is when one blogger nominates another blogger for a blog award called the Versatile Blogger Award. It comes with a set of rules. A wonderful fellow blogger, 1stjoeyanna, nominated our site for the versatile blogger award. On behalf of our site, I would like to thank 1stjoeyanna very much for this tremendous honor which has made us very happy.

Versatile blogger Nomination:

Versatile Blogger Nomination

The Versatile blogger Nomination has the following rules:
1) Thank the blogger who nominated – Thank you, 1stjoeyanna
2) Nominate 15 fellow bloggers and tell them that you nominated their site
3) List seven facts about you

Our site nominates the following bloggers for their superb sites. We are only allowed 15 or we would have listed all the wonderful sites we enjoy.
1) fifthfoodhealthprogram
2) everysensory
3) Wu Ka Ling
4) Will Bigg
6) somethinghigher
7) gentlemen of sport
8) getPHYT
9) Tedious Ted
10) The Caffeinated Witch
11) Chrysty K. Sanders
12) Ezza
13) onlyjustcrazy
14) dance healthier
15) The Beat Daily
Honorable mention to:
health demystified
gouldie girl
nyrva
Athur Mani Tutorials: Architecture and the Built Environment
foodloveandbonding
Therapy book

Seven facts about this site:
1) We write about what we care about deeply
2) We write about Autism Spectrum Disorder research
3) We write about natural nutrition
4) We write about the flu vaccine and each year’s composition
5) We write about Auto-immune diseases and connections between family members, if any
6) We write about food, recipes, health and obesity
7) Above all, we write about the G protein and how they might hold the answer to Allergy, Autism, Aspesrgers and Autoimmune disease.

We hope you visit our site often. We would love to hear from you. Do also visit the 15 sites we listed and our wonderful fellow blogger 1stjoeyanna, who nominated our site so generously. Happy blogging to all of you!

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List of Autism 2012 Events in USA: Walk or Speak for Autism


Autism is the fastest-growing serious developmental disorder in the U.S. – we need more volunteers
Whether this is your first walk or the 10th, take the first step and register today.
Every 11 minutes, another family receives the devastating news that their child has an autism spectrum disorder. Help us change that! Start fundraising today. Whether you strive to join our new “Grand Club” (walkers that raise $1,000 or more) or sell lemonade to boost your total or create your own unique event, you become a part of the solution! Don’t wait another minute – start a corporate, school or family team today!

The Autism 5K, May 19th, 2012:

Run/Walk

Lake Calhoun, in Minneapolis, MN – open to all.

2012 Autism 5K race proceeds will benefit local families affected by autism

2012 Chicago Walk Now for Autism Speaks
Saturday, May 12, 2012
You will not only raise funds, but you will become a part of a fun and supportive family-focused community.

Ala Moana Beach Park in Honolulu on Saturday, April 21st, 2012 for the 7th annual Hawaii Walk Now for Autism Speaks

2012 Cincinnati: Walk Now for Autism Speaks
Saturday, May 19, 2012
Please check back soon for more information on how YOU can register for the first annnual Autism Speaks Puzzle Run on Saturday, October 20!

Add your 2012 Autism event in comment section and it will be uploaded here.

Related Articles
How to prepare college professors for a student with Rheumatoid Arthritis, Aspergers and Auto-immune disease.

National TV channel PBS asks two prominent scientists in six series – why is Autism rising?
Autistic child and Multiple Sclerosis parent – A connection?
Studies linking Autism to Obesity during pregnancy – limited to Autoimmune disease?

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“What worries me”: A variety list of 7 posts including this phrase


I wondered how many people are worried and what worries them. Here is a list that I found. Frank Sinatra has a song with lyrics of the song including this phrase and a link leading to a free download for your mobile phone ring is below. There is also a video about worrying about Law School. There is a worry about Orioles trading, Crowd Sourcing, Finding the right man, and more.

Feel free to add your “What worries me” in the comments and share your worry with us.  Especially, about Autism, Aspergers and Allergy and other Autoimmune diseases like Multiple Sclerosis and Juvenile and Adult Rheumatoid Arthritis. Diabetes and Obesity.

Sorrow and worries shared is sorrow and worries halved
Happiness shared is happiness doubled

Together we can halve our worries.

“What worries me”: List of sites in virtual space including this phrase. It is not comprehensive.
1) An email: What worries me is, will we be able to find guys who have a similar thinking process? Tejaswee’s Blog
2) It Worries Me Lyrics
Frank Sinatra

3) That’s What Worries Me
by DAVE SCHULER on APRIL 3, 2012
discussing the bankruptcy of the solar company with the largest grant from DOE
4) What Worries Me About the Crowdfunding Initiatives
Posted: 03/ 8/2012
6:43 pm by Tim Berry, President and Chairman, Palo Alto Software, in Huffington Post
5) Dan Lyons Mar 20, 2012 – What worries me is that now that Daisey has been discredited, people will think that all of this stuff about bad conditions in China was made up, …in The US News with the Title: The True Victims of Mike Daisey’s Lies May Be Those Chinese Workers He Championed
6) What worries me by Andrew Ge in Camden Chat on Feb 7, 2012 – The Baltimore Orioles’ trade of Jeremy Guthrie feels both fair and underwhelming all at once. Are the Orioles in a perpetual cycle of failing to …
7) One Less Worry: What worries me about Law School. A wonderful video. This is a video submission to the Access Group One Less Worry competition and had 825 views to date.

Worries added by our readers:

I also think that mental illness – depression and severe stress – is a serious issue in the legal profession in Australia, and has recently received quite a bit of publicity especially in the Australian law schools.
Author: Wendy, versatile blogger of somethinghigher.

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High Fructose corn syrup – why would anyone educated still consume it?


Two scientifically researched and published papers show the connection between consumption of high fructose corn syrup and NAFLD. One is a review published in Nature reviews and the other a research paper of a three year study. A third research group says that high fructose corn syrup should be declared an environmental toxin. A fourth paper publised by a team of nutritionists in the American Journal of Clinical Nutrition in 2004, suggest that the obesity epidemic trend since 1970s is closely related to 1000 fold increase in use of high fructose corn syrup in sweetened beverages. This article has already been cited over 800 times by 2012. Click here to read. Why are these international research teams concerned about the rising public health concern of NAFLD?

1) The review postulates that the Western diet which includes excessive fructose may be leading to Nonalcoholic fatty liver disease (NAFLD). Which means that liver damage from excessive consumption of alcohol is expected. However, nonalcoholics are often diagnosed with liver damage. These reviewersblame their western diet which includes beverages sweetened with high fructose corn syrup. The damage is in two steps and the second step can be prevented with antioxidants. However, the western diet does not include or is deficient in antioxidants. The combination of high fructose and lack of antioxidants may be contributing to the most frequent liver disease worldwide – NAFLD. To learn more about the toxic effects of sweeteners you may want to write to one of the authors of this review and ask for a copy of a latest february 2012 article in journal Nature entitled:

Public health: The toxic truth about sugar.

Department of Pediatrics, University of California, San Francisco, California 94143, USA. rlustig@peds.ucsf.edu

2) Another group of researchers (Liver Unit, Ziv Medical Center, Safed, Israel and other colleagues)were perplexed when faced with patients with fatty liver when they did not have the traditional risk factors such as obesity, diabetes and hyperlipidemia. So, they conducted a three year, systematic scientific research study with patients with fatty liver and healthy people (controls) with no fatty liver. They used a validated food questionnaire given by a dietician. They followed the daily intake of food and beverages and sources of added sugar. Their results?

80% of the patients with fatty liver consumed sweetened beverages compared to 20% of healthy people. They included 50grams per day of added sugar to their beverages which was considered excessive by the researchers and 40% of the patients with fatty liver consumed four of more of such beverages which were excessively sweetened. Ultrasound findings revealed mild fatty liver in 44% of the cases to severe fatty liver in 18% of the cases.

Soft drink beverage was the only independent variable able to predict a fatty liver in 82.5% of cases.

If you want to encourage more research on such topics encourage these scientists with your words or funding. Write to them at:

Correspondence: Dr Nimer Assy, Liver Unit, Ziv Medical Center, PO Box 1008, Safed 13100, Israel. Telephone 9-724-682-8441, fax 9-724-682-8442, e-mail assy.n@ziv.health.gov.il or ; Email: assy.nimer@gmail.com

Their conclusion is obvious isn’t it? Change your beverage habit. Unsweeten it. If you cannot stop it yourself, just do not introduce your child to sugar or corn syrup sweetened beverages from childhood. The child will never crave a sweetened beverage and prefer plain water, like our healthier ancestors.

3) A third group of researchers say that high fructose corn syrup depletes ATP and causes uric acid to collect in human bodies. They say it is an environmental toxin. Write to this research team to learn more or if you wish to encourage them for further research on the effect of fructose on renal biology and disease.
Johnson RJ, Sanchez-Lozada LG, Nakagawa T.
Division of Renal Diseases and Hypertension, University of Colorado, Aurora, Colorado 80045, USA.
Email: richard.johnson@ucdenver.edu

Question for our readers: What is used to sweeten beverages today? High fructose corn syrup. Is it better than sugar? If yes, why?

To our readers: If you know of a single healthy benefit of high fructose corn syrup, please share it with our readers.
If you are aware of any human health features improved by substituting sugar used for centuries with high fructose corn syrup introduced in recent decades, please share with our readers.

If you cannot stop yourself from having sweetened beverages, just do not introduce your child to sugar or corn syrup sweetened beverages from childhood. Children develop taste buds as infants. The child will probably never crave a sweetened beverage and prefer plain water, like our healthier ancestors. You may want to write to the pediatricians and scientists listed above and ask why they are concerned of this rising public health threat. The more informed you are, the better you can serve your community and prevent it from facing cripling medical expenses in the near future.

If you liked this, you may also enjoy:

1) Diabetes is an Autoimmune Disease

2) Know your G proteins. One of a series of state-of-the-art articles to be posted here to inform you on the roles of G proteins in human health. Over 30% of medicines today aim for your G proteins for therapy and the newer ones are inter-related to your G proteins. If you want to be current in therapy, you would want to know your G proteins.

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Why and how to add Calcium in the diet of a person with Autism Spectrum Disorder


Cells in the brain contain proteins called calcium channels that can regulate Calcium levels within the cells. Calcium levels inside the cells are 10,000 fold lower than Calcium levels outside the cells. The calcium channels are gate keepers of Calcium, allowing only the required amount inside the cell by opening briefly and then the gate shuts. Calcium cannot be changed or transformed by the body, which makes it imperative to regulate calcium levels inside the cells, to prevent it’s build up at toxic levels.

Gene mutation: A mutation in the gene for these gate proteins can alter their structure causing them [calcium gates] to stay open much longer than usual. This allows calcium to continue to enter inside the cell abnormally. The result? An overload of Calcium inside the cell. It is a novel disorder characterized by autism and other features. Read more about the CACNA1C gene and CaV1.2 Calcium channel, for information on where to find geneticists, disease manaagement & therapy and additional information.

Inheritance of calcium channel disorder: Most cases of this calcium channel (CaV1.2) disorder is inherited by a new mutation (G406R) with no previous history of this altered gene in their family.

Possible therapy? Although, the role of this calcium channel as important for the contraction of the heart is known, its role within the cell is not well understood, yet. The disorder is caused by an inability of these Calcium gates to close. What does that result in? Yes, a Calcium overload inside the cells. This also suggested to the researchers that Calcium channel blockers may be useful for treating this disorder.

Researchers: This discovery by Dr Igor Splawski and colleagues demonstrates the importance of Calcium imbalance and established the importance of Calcium in human development and implicates Calcium in cell signaling and Autism.

Did you appreciate this research on Calcium channels? Then, do write to Dr Igor Splawski and let him know that. Email: igor@enders.tch.harvard.edu or Snail mail: Department of Cardiology, Children’s Hospital, Departments of Pediatrics and Cell Biology, Harvard Medical School and Howard Hughes Medical Institute, Boston, MA 02115 USA. Invite him or his colleagues to discuss the role of Calcium channels in Autism or human development. You will really enjoy his contribution to community – he has over 30 patents.

Although, the gene mutation causes this disorder, it is also clear that too much Calcium cannot be good for a human. That is why, it should not surprise anyone who has read Dr Igor Splawski’s teams’ research papers to learn about other issues when a person eats too much Calcium. Have you heard of women breaking their femur bone in their leg? You will also learn that they regularly have high doses of Calcium supplements to prevent osteoporosis or bone loss in women as they age. It is unclear why eating natural sources of Calcium is safe while eating Calcium in excessive supplement form might cause bones to break.

Related Article
Too much Calcium can break nails and bones
Four facts about Allergy
Know your G proteins – Autism
Studies linking Autism to obesity during pregnancy – too limited?

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G proteins: the connector proteins that try to prevent Autism Spectrum Disorder


Prof Mark Rasenick’s team in Chicago, Dr Gunner Schulte team in Sweden, and teams of experts all over the world like Dr Robert, Dorsam and Dr Silvio Gutkind, in Universities and industries are studying the G proteins in the developing and degenerating brain. They have a theory that if they understand how the G proteins work, they can cure a number of brain issues. In G proteins may lie an answer on how to cure Autism Spectrum Disorder and also, how to prevent it in the future.

G proteins are made of three proteins named alpha, beta and gamma. There are many different kinds of alpha, beta and gamma proteins and they can combine in many different ways. So, how many kinds of G proteins can there be? Many and more are being discovered. What is the function of the G proteins? They are connectors.

The G protein made up of alpha, beta and gamma proteins

Everyone knows that a connector is either a person who knows a lot of people who know lots more people or a connector is a valve that interconnects two tubes. Similarly, a G protein is a connector. It makes things happen within people. A person is made up of many, many cells, carrying genetic information. Inside each cell, in addition to genes are many different kinds of G proteins. When the cell gets a signal, its genes respond. Well, how does a signal outside the cell get to the genes inside the cell to tell it to respond? The G proteins. They interconnect the protein that receives the signal with the protein that activates the gene.

Now, let’s imagine the human gene receives a signal to die, because the signal was a severe toxin. Does the human being die? No, because survival is a crucial cell behavior. So, for a human being to die, many genes in many cells have to receive a signal to die. Which means, when the human is stimulated by a specific combination of signals rather than a single signal acting alone, only then does the cell collect the information coming from separate signals, integrates this information, and then makes a proper response – to die. The cell may also receive a similar integrated signal for another important human event – to grow and divide and to live. This integration is equivalent to microprocessors in a computer.

G protein connected receptor: When a human smells something or gets an infection or touches a chemical, a signal is received and processed ultimately by the brain. The human responds by “liking” the smell, or “succumbing” or “resisting” the infection or getting a chemical reaction. How does a signal in the environment reach the brain? Signals are received by proteins on the cell surface, called receptors. Within the cell are G proteins which connect these receptors to their target enzyme or ion channel, which ultimately tell the genes how to respond. You would expect a defective G protein to mess up a signal pathway. This is prevented because there appears to be “back up” G proteins which can take care of connector functions to keep the cell’s crucial functions going smoothly. To view a schematic in the journal Nature Reviews Cancer by Drs Robert T. Dorsam and J. Silvio Gutkind click here. It beautifully illustrates how G proteins integrate several receptors receiving many signals through several secondary messengers.

This schematic will also explain why answers to question “which signal causes 1 in 88 or 100 children have autism today” cannot be answered by just one factor like obesity or SHANK gene mutation or An aging father or a G protein mutation.

Second Messengers: Most G protein connected receptors activate a chain of events that alters the concentration of one or more small signaling molecules inside the cell. These second messengers in turn, pass the signal on by altering the behavior of selected cellular proteins. One very widely used second messenger is Calcium, stimulated by a distinct G-protein connected pathway. Another widely used second messenger is Cyclic AMP.

When a hormone is the chemical that acts as a signal the response is via second messenger Cyclic AMP.
When G proteins receive a signal to connect to another crucial enzyme – phospholipase C, then it changes the concentration of calcium within the cell, which is a far more widely used second messenger than Cyclic AMP.

In the next article I will reveal how calcium signaling works or as relevant to Autism – does not work.

An expert on G-protein of the brain:
There are many scientists in the world who are working on the G protein. Do reach out to them and request them to speak on their work and explain their focus.
1) Dr Gunnar Schulte and colleagues
Department of Physiology and Pharmacology, Karolinska Institutet, S-171 77 Stockholm, Sweden.
Email: gunnar.schulte@fyfa.ki.se

2) MARK M. RASENICK

Prof. Mark M. Rasenick

Professor

Physiology and Biophysics, and Psychiatry

Director, Biomedical Neuroscience Training Program, U. Illinois College of Medicine, Chicago, IL 60612

Cytoskeletal modulation of neuronal signal transduction

http://www.uic.edu/depts/mcpb/pages/rasenick/rasenick.htm

Related Articles:
Know your G proteins
Studies linking obesity to Autism
Why is Autism observed in America and not in a developing country like Somalia
Autistic child and a multiple sclerosis parent – a connection?

I wish to thank two of my readers:

1)  Everysensory blogger for inspiring me to cover the “whole” picture when the media suddenly focussed on “obesity causes Autism”.

2)  Fitfoodhealthprogram blogger who inspired me to write more information filled articles related Autism.

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Could anti-CD20 cure Type 2 – Diabetes? Stanford U. and U. Toronto researchers ask today


Researchers who have studied obesity and diabetes asked if both these diseases could be termed autoimmune diseases and  announced today that Type 2 – diabetes can be termed autoimmune disease and it causes obesity.  The human version of anti-CD20, called rituximab, is already FDA-approved to treat some blood cancers and autoimmune disorders. Which may lead to an interesting inquiry: Could this FDA – approved treatment for autoimmune disorders also treat some cases of obesity and all cases of Type 2-diabetes? Published in two articles in Nature medicine, one today and one earlier.

Two excerpts:
Quote

According to co-first author Daniel Winer, MD:

This work will change the way people think about obesity, and will likely impact medicine for years to come as physicians begin to switch their focus to immune-modulating treatments for type-2 diabetes.
Unquote

Quote

Type-2 diabetes is characterized by the gradual development of insulin resistance, which affects the ability of the body to properly metabolize glucose. It’s associated with being overweight, but it can also have a genetic component. Despite the fact that millions of people have type-2 diabetes, the root cause of the insulin resistance is not known. In 2009, Daniel and Shawn Winer showed (also in Nature Medicine; subscription required) that T cells of the immune system were involved. Now they found that another immune cell, called a B cell, also plays an important role.

Unquote

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Type 2 – Diabetes is an Autoimmune disease – say Stanford researchers today; role in Autism?


Stanford researchers, Dr Edgar Engelmann and colleagues redefine Type 2 – Diabetes today as an Autoimmune disease. Autism in children is higher in families and pregnant mothers with Autoimmune diseases. This connection too is being further researched by immunologists studying Autism today.

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Studies linking Autism to obesity during pregnancy: limited to mothers with autoimmune diseases?


Since Dr. Paula Krakowiak, of University of California, Davis, published an article on a significant link between an obese pregnant mother and an Autistic child, the media is running with this information. However, what the media should also add is that no single factor alone appears to be linked to Autism but a combination of factors such as an older father or mother, new gene mutations , or diabetes which were not present in the grand parents but appear in the parents, accounting for about 70% of Autism Spectrum Disorder cases and of course, the vaccine connection debate, in addition to the Somali cases of Autism in Minnesotta (Vit D rather than obesity perhaps?) are various other factors which together or in combination with unknown environmental factors like herbicides perhaps cause Autism.

A pregnant mother preparing for her baby

Autoimmune disease and Autism: It might be timely to add that Dr Thayne Sweeten and colleagues have found that families with other Autoimmune diseases have higher cases of Autism. They strongly suggest that immune and autoimmune factors might play a role in causing Autism in a child.

Where the obese pregnant mothers diabetic: Now, you might ask: Did the pregnant obese mothers who produced an Autistic child have an autoimmune disease? The answer may very well be yes! If so, you may ask if that disease was Diabetes, becauses it causes a person to be obese. The answer may very well be yes! May be another autoimmune disease too like Rheumatoid Arthritis perhaps.

The reason I request you to ask this question about an autoimmune disease in the pregnant obese mother is because just today Stanford University researchers led by Dr Edgar Engelmann have announced in Nature Medicine that Type 2 – Diabetes is being redefined an autoimmune disease.

Naturally, this changes the direction of Diabetes research to what factor trigger the autoimmune reaction in patients to cause Type 2 – Diabetes. Also, are these the same factors that cause an Autistic child to be produced from an obese pregnant mother?

Thank  you, blogger kristashealthylife for alerting us to the article linking obesity during pregnancy to Autism. It is why I wrote this article.

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